Recently, a number of genome-wide affiliation research recognized PHACTR1 as key locus for 5 numerous vascular issues: coronary artery disease, migraine, fibromuscular dysplasia, cervical artery dissection and hypertension. Although these signify important threat components or comorbidities for ischemic stroke, PHACTR1 function in mind small vessel ischemic disease and ischemic stroke most vital survival mechanism, such because the recruitment of mind collateral arteries like posterior speaking arteries (PcomAs), stays unknown.
Therefore, we utilized exome and genome sequencing in a multi-ethnic cohort of 180 early-onset unbiased familial and apparently sporadic mind small vessel ischemic disease and CADASIL-like Caucasian patients from US, Portugal, Finland, Serbia and Turkey and in 2 C57BL/6J stroke mouse fashions (bilateral widespread carotid artery stenosis [BCCAS] and center cerebral artery occlusion [MCAO]), characterised by totally different levels of PcomAs patency. We report three very uncommon coding variants in the small vessel ischemic disease-CADASIL-like cohort (p.Glu198Gln, p.Arg204Gly, p.Val251Leu) and a stop-gain mutation (p.Gln273*) in one MCAO mouse.
These coding variants do not cluster in PHACTR1 identified pathogenic domains and are not prone to play a critical function in small vessel ischemic disease or mind collateral circulation. We additionally exclude the chance that replicate quantity variants (CNVs) or a variant enrichment in Phactr1 could also be related to PcomA recruitment in BCCAS mice or linked to numerous vascular traits (cerebral blood move pre-surgery, PcomA measurement, leptomeningeal microcollateral size and junction density throughout mind hypoperfusion) in C57BL/6J mice, respectively.
Genetic variability in PHACTR1 is not prone to be a standard susceptibility issue influencing small vessel ischemic disease in patients and PcomA recruitment in C57BL/6J mice. Nonetheless, uncommon variants in PHACTR1 RPEL domains could affect the stroke final result and are price investigating in a bigger cohort of small vessel ischemic disease patients, totally different ischemic stroke subtypes and with purposeful research.
Insight of fetal to grownup hemoglobin change: Genetic modulators and therapeutic targets
The medical heterogeneity of β-hemoglobinopathies is so variable that it prompted the researchers to determine the genetic modulators of those ailments. Though the first modulator is the kind of β-globin mutation which impacts the diploma of β-globin chain synthesis, the co-inheritance of α-thalassemia and the fetal hemoglobin (HbF) ranges additionally act as potent secondary genetic modifiers.
As elevated HbF ranges ameliorate the severity of hemoglobinopathies, in this evaluate, the genetic modulators mendacity inside and outdoors the β-globin gene cluster with their believable function in governing the HbF ranges have been summarised, which in future could act as potential therapeutic targets.
Genetic affiliation of MMP14 promoter variants and their purposeful significance in gallbladder most cancers pathogenesis
Gallbladder most cancers (GBC) is comparatively uncommon however exhibits excessive frequency in sure geographical areas and ethnic teams, which embrace Northern and Eastern states of India. Previous research in India have indicated the doable function of genetic predisposition in GBC pathogenesis. Although matrix metalloproteinase-14 (MMP14) is identified modulator of tumour microenvironment and tumorigenesis and TCGA information additionally suggests its upregulation but, its function in genetic predisposition for GBC is utterly unknown.
We explored MMP14 promoter genetic variants as threat components and their implication in expression modulation and the pathogenesis of GBC. We genotyped all single nucleotide polymorphisms of MMP14 promoter by Sanger’s sequencing in roughly 300 GBC and 300 management examine topics of Indian ethnicity and, in 26 GBC tissue samples. Protein expression of MMP14 in GBC tissue samples was checked by immunohistochemistry. In vitro luciferase reporter assay was carried out to elucidate function of promoter genetic variants on expression ranges in two totally different cell traces.
MMP14 promoter variants, rs1003349 (p worth = 0.0008) and rs1004030 (p worth = 0.0001) have been considerably related to GBC. Luciferase reporter assay confirmed excessive expression for threat alleles of each the SNPs. Genotype-phenotype correlation for rs1003349 and rs1004030, in affected person pattern, confirmed that threat allele carriers had increased expression ranges of MMP14; furthermore, the correlation sample matched with genetic affiliation fashions. Overall, this examine unravels the affiliation of MMP14 promoter SNPs with GBC which contribute to pathogenesis by rising its expression.
Compact Genetic Algorithm-based Feature Selection for Sequence-based Prediction of Dengue-Human Protein Interactions
Dengue Virus (DENV) an infection is one of many quickly spreading mosquito-borne viral infections in people. Every yr, round 50 million folks get affected by DENV an infection, ensuing in 20,000 deaths. Despite the latest experiments specializing in dengue an infection to know its performance in the human physique, a number of functionally vital DENV-human protein-protein interactions (PPIs) have remained unrecognized. This article presents a mannequin for predicting new DENV-human PPIs by combining totally different sequence-based options of human and dengue proteins just like the amino acid composition, dipeptide composition, conjoint triad, pseudo amino acid composition, and pairwise sequence similarity between dengue and human proteins.
A Learning vector quantization (LVQ)-based Compact Genetic Algorithm (CGA) mannequin is proposed for characteristic subset choice. CGA is a probabilistic approach that simulates the habits of a Genetic Algorithm (GA) with lesser reminiscence and time necessities. Prediction of DENV-human PPIs is carried out by the weighted Random Forest approach because it is discovered to carry out higher than different classifiers. We have predicted 1013 PPIs between 335 human proteins and 10 dengue proteins.
CytoSelect™ LDH Cytotoxicity Assay Kit |
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| CBA-241 | Cell Biolabs | 960 assays | EUR 320 |
CytoSelect™ Leukocyte Transmigration Assay |
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| CBA-212 | Cell Biolabs | 24 assays | EUR 670 |
CytoSelect™ MTT Cell Proliferation Assay |
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| CBA-252 | Cell Biolabs | 960 assays | EUR 320 |
CytoSelect™ 24-well Cell Migration Assay (8 μm), Colorimetric |
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| CBA-100 | Cell Biolabs | 12 assays | EUR 480 |
CytoSelect™ 24-well Cell Migration Assay (8 μm), Colorimetric |
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| CBA-100-5 | Cell Biolabs | 5 x 12 assays | EUR 2180 |
CytoSelect™ 24-well Cell Migration Assay (8 μm), Fluorometric |
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| CBA-101 | Cell Biolabs | 12 assays | EUR 480 |
CytoSelect™ 24-well Cell Migration Assay (8 μm), Fluorometric |
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| CBA-101-5 | Cell Biolabs | 5 x 12 assays | EUR 2180 |
CytoSelect™ 96-well Cell Migration Assay (8 μm), Fluorometric |
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| CBA-106 | Cell Biolabs | 96 assays | EUR 580 |
CytoSelect™ 96-well Cell Migration Assay (8 μm), Fluorometric |
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| CBA-106-5 | Cell Biolabs | 5 x 96 assays | EUR 2535 |
CytoSelect™ 24-well Wound Healing Assay |
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| CBA-120 | Cell Biolabs | 24 assays | EUR 595 |
CytoSelect™ 24-well Wound Healing Assay |
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| CBA-120-5 | Cell Biolabs | 5 x 24 assays | EUR 2465 |
CytoSelect™ BrdU Cell Proliferation ELISA Kit |
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| CBA-251 | Cell Biolabs | 96 assays | EUR 455 |
CytoSelect™ Tumor Transendothelial Migration Assay |
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| CBA-216 | Cell Biolabs | 24 assays | EUR 670 |
CytoSelect™ Cell Viability and Cytotoxicity Assay |
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| CBA-240 | Cell Biolabs | 96 assays | EUR 305 |
CytoSelect™ 96-well Cell Transformation Assay |
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| CBA-130 | Cell Biolabs | 96 assays | EUR 640 |
CytoSelect™ 96-well Cell Transformation Assay |
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| CBA-130-5 | Cell Biolabs | 5 x 96 assays | EUR 2695 |
CytoSelect™ 96-well Phagocytosis Assay (Zymosan) |
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| CBA-224 | Cell Biolabs | 96 assays | EUR 620 |
CytoSelect™ 96-well Phagocytosis Assay (Zymosan) |
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| CBA-224-5 | Cell Biolabs | 5 x 96 assays | EUR 2670 |
CytoSelect™ 24-Well Cell Co-Culture System |
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| CBA-160 | Cell Biolabs | 24 assays | EUR 365 |
CytoSelect™ 24-Well Cell Co-Culture System |
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| CBA-160-5 | Cell Biolabs | 5 x 24 assays | EUR 1585 |
CytoSelect™ 48-Well Cell Contraction Assay Kit |
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| CBA-5021 | Cell Biolabs | 48 assays | EUR 575 |
CytoSelect™ Cell Proliferation Assay Reagent (Colorimetric) |
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| CBA-253 | Cell Biolabs | 10 mL | EUR 320 |
CytoSelect™ 24-well Cell Haptotaxis Assay (8 µm), FN-coated, Colorimetric |
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| CBA-100-FN | Cell Biolabs | 12 assays | EUR 505 |
CytoSelect™ 24-well Cell Haptotaxis Assay (8 µm), FN-coated, Fluorometric |
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| CBA-101-FN | Cell Biolabs | 12 assays | EUR 505 |
CytoSelect™ 24-Well Wound Healing Assay, Trial Size |
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| CBA-120-T | Cell Biolabs | 6 assays | EUR 295 |
CytoSelect™ 24-well Cell Haptotaxis Assay (8 µm), COL-coated, Colorimetric |
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| CBA-100-COL | Cell Biolabs | 12 assays | EUR 505 |
CytoSelect™ 24-well Cell Haptotaxis Assay (8 µm), COL-coated, Fluorometric |
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| CBA-101-COL | Cell Biolabs | 12 assays | EUR 505 |
CytoSelect™ 24-well Collagen Cell Invasion, Colorimetric |
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| CBA-110-COL | Cell Biolabs | 12 assays | EUR 535 |
CytoSelect™ 96-well Leukocyte-endothelium Adhesion Kit |
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| CBA-210 | Cell Biolabs | 100 assays | EUR 495 |
CytoSelect™ 96-well Phagocytosis Assay (Red Blood Cell) |
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| CBA-220 | Cell Biolabs | 96 assays | EUR 540 |
CytoSelect™ 24-well Anoikis Assay (Colorimetric/Fluorometric) |
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| CBA-080 | Cell Biolabs | 24 assays | EUR 505 |
CytoSelect™ 96-well Anoikis Assay (Colorimetric/Fluorometric) |
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| CBA-081 | Cell Biolabs | 96 assays | EUR 525 |
CytoSelect™ 24-Well Cell Migration Assay (8 µm, Colorimetric Format), Trial Size |
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| CBA-100-T | Cell Biolabs | 4 assays | EUR 240 |
CytoSelect™ 24-Well Cell Migration Assay (8 µm, Fluorometric Format), Trial Size |
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| CBA-101-T | Cell Biolabs | 4 assays | EUR 240 |
CytoSelect™ 24-well Collagen Cell Invasion Assay, Fluorometric |
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| CBA-111-COL | Cell Biolabs | 12 assays | EUR 535 |
CytoSelect™ 96-well Collagen Cell Invasion Assay, Fluorometric |
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| CBA-112-COL | Cell Biolabs | 96 assays | EUR 705 |
CytoSelect™ 24-well Cell Migration Assay (5 μm), Fluorometric |
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| CBA-102 | Cell Biolabs | 12 assays | EUR 480 |
CytoSelect™ 24-well Cell Migration Assay (5 μm), Fluorometric |
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| CBA-102-5 | Cell Biolabs | 5 x 12 assays | EUR 2180 |
CytoSelect™ 24-well Cell Migration Assay (3 μm), Fluorometric |
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| CBA-103 | Cell Biolabs | 12 assays | EUR 480 |
CytoSelect™ 24-well Cell Migration Assay (3 μm), Fluorometric |
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| CBA-103-5 | Cell Biolabs | 5 x 12 assays | EUR 2180 |
CytoSelect™ 96-well Cell Migration Assay (3 μm), Fluorometric |
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| CBA-104 | Cell Biolabs | 96 assays | EUR 580 |
CytoSelect™ 96-well Cell Migration Assay (3 μm), Fluorometric |
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| CBA-104-5 | Cell Biolabs | 5 x 96 assays | EUR 2535 |
CytoSelect™ 96-well Cell Migration Assay (5 μm), Fluorometric |
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| CBA-105 | Cell Biolabs | 96 assays | EUR 580 |
CytoSelect™ 96-well Cell Migration Assay (5 μm), Fluorometric |
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| CBA-105-5 | Cell Biolabs | 5 x 96 assays | EUR 2535 |
CytoSelect™ 24-well Cell Migration Assay (12 μm), Colorimetric |
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| CBA-107 | Cell Biolabs | 12 assays | EUR 480 |
CytoSelect™ 24-well Cell Migration Assay (12 μm), Fluorometric |
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| CBA-108 | Cell Biolabs | 12 assays | EUR 480 |
CytoSelect LDH Cytotoxicity Assay Kit |
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| MBS168668-5x960Assays | MyBiosource | 5x960Assays | EUR 2180 |
CytoSelect LDH Cytotoxicity Assay Kit |
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| MBS168668-960Assays | MyBiosource | 960Assays | EUR 475 |
CytoSelect™ 24-well Cell Migration and Invasion Assay (8 µm), Colorimetric, Combo Kit |
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| CBA-100-C | Cell Biolabs | 2 x 12 assays | EUR 915 |
CytoSelect™ 24-well Cell Migration and Invasion Assay (8 µm), Colorimetric, Combo Kit |
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| CBA-100-C-5 | Cell Biolabs | 10 x 12 assays | EUR 3950 |
CytoSelect™ 24-well Cell Migration and Invasion Assay (8 µm), Fluorometric, Combo Kit |
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| CBA-101-C | Cell Biolabs | 2 x 12 assays | EUR 915 |
CytoSelect™ 96-well Cell Migration and Invasion Assay (8 µm), Fluorometric, Combo Kit |
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| CBA-106-C | Cell Biolabs | 2 x 96 assays | EUR 1080 |
CytoSelect 24-well Cell Migration Assay (8 um), Colorimetric |
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| MBS168121-12Assays | MyBiosource | 12Assays | EUR 660 |
CytoSelect 24-well Cell Migration Assay (8 um), Colorimetric |
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| MBS168121-5x12Assays | MyBiosource | 5x12Assays | EUR 2625 |
CytoSelect 24-well Cell Migration Assay (8 um), Fluorometric |
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| MBS168379-12Assays | MyBiosource | 12Assays | EUR 660 |
CytoSelect 24-well Cell Migration Assay (8 um), Fluorometric |
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| MBS168379-5x12Assays | MyBiosource | 5x12Assays | EUR 2625 |
CytoSelect 96-well Cell Migration Assay (8 um), Fluorometric |
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| MBS168842-5x96Assays | MyBiosource | 5x96Assays | EUR 3015 |
CytoSelect 96-well Cell Migration Assay (8 um), Fluorometric |
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| MBS168842-96Assays | MyBiosource | 96Assays | EUR 775 |
CytoSelect IdU Competitive ELISA Kit |
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| CBA-5100 | Cell Biolabs | 96 assays | EUR 651.6 |
CytoSelect EdU Competitive ELISA Kit |
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| CBA-5101 | Cell Biolabs | 96 assays | EUR 651.6 |
CytoSelect™ 48-well Cell Adhesion Assay (Fibronectin, Colorimetric) |
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| CBA-050 | Cell Biolabs | 48 assays | EUR 370 |
CytoSelect™ 48-well Cell Adhesion Assay (Fibronectin, Fluorometric) |
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| CBA-051 | Cell Biolabs | 48 assays | EUR 400 |
CytoSelect™ 24-well Cell Invasion (Basement Membrane), Fluorometric |
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| CBA-111 | Cell Biolabs | 12 assays | EUR 535 |
CytoSelect BrdU Competitive ELISA Kit |
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| CBA-5098 | Cell Biolabs | 96 assays | EUR 651.6 |
CytoSelect Leukocyte Transmigration Assay |
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| MBS168158-24Assays | MyBiosource | 24Assays | EUR 880 |
CytoSelect Leukocyte Transmigration Assay |
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| MBS168158-5x24Assays | MyBiosource | 5x24Assays | EUR 4060 |
CytoSelect™ 48-well Cell Adhesion Assay (Collagen I, Colorimetric) |
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| CBA-052 | Cell Biolabs | 48 assays | EUR 370 |
CytoSelect™ 48-well Cell Adhesion Assay (Collagen I, Fluorometric) |
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| CBA-053 | Cell Biolabs | 48 assays | EUR 400 |
CytoSelect™ 48-well Cell Adhesion Assay (Collagen IV, Colorimetric) |
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| CBA-060 | Cell Biolabs | 48 assays | EUR 370 |
CytoSelect™ 48-well Cell Adhesion Assay (Collagen IV, Fluorometric) |
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| CBA-061 | Cell Biolabs | 48 assays | EUR 400 |
CytoSelect MTT Cell Proliferation Assay |
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| MBS168154-5x960Assays | MyBiosource | 5x960Assays | EUR 2180 |
CytoSelect MTT Cell Proliferation Assay |
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| MBS168154-960Assays | MyBiosource | 960Assays | EUR 475 |
CytoSelect™ 96-Well Phagocytosis Assay (E. coli, Colorimetric Format) |
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| CBA-222 | Cell Biolabs | 96 assays | EUR 595 |
CytoSelect 24-well Wound Healing Assay |
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| MBS168434-24Assays | MyBiosource | 24Assays | EUR 790 |
CytoSelect 24-well Wound Healing Assay |
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| MBS168434-5x24Assays | MyBiosource | 5x24Assays | EUR 2935 |
CytoSelect 24-well Wound Healing Assay |
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| MBS168434-6Assays | MyBiosource | 6Assays | EUR 445 |
CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Colorimetric |
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| CBA-135 | Cell Biolabs | 96 assays | EUR 715 |
CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Colorimetric |
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| CBA-135-5 | Cell Biolabs | 5 x 96 assays | EUR 3095 |
CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Fluorometric |
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| CBA-140 | Cell Biolabs | 96 assays | EUR 750 |
CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Fluorometric |
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| CBA-140-5 | Cell Biolabs | 5 x 96 assays | EUR 3215 |
CytoSelect™ 24-well Cell Invasion Assay (Basement Membrane), Colorimetric |
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| CBA-110 | Cell Biolabs | 12 assays | EUR 535 |
CytoSelect™ 96-well Cell Invasion Assay (Basement Membrane), Fluorometric |
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| CBA-112 | Cell Biolabs | 96 assays | EUR 705 |
CytoSelect™ 96-Well Hematopoietic Colony Forming Cell Assay (96 assays) |
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| CBA-320 | Cell Biolabs | 96 assays | EUR 440 |
CytoSelect™ 24-Well Cell Contraction Assay Kit (Floating Matrix Model) |
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| CBA-5020 | Cell Biolabs | 24 assays | EUR 495 |
CytoSelect Tumor-endothelium Adhesion Assay |
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| CBA-215 | Cell Biolabs | 100 assays | EUR 692.4 |
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Description: Leukocyte or tumor cell interactions with vascular endothelium consist of a cascade of processes including the firm attachment of cells to endothelial cell adhesion molecules. The CytoSelect Tumor Endothelium Adhesion Assay provides a robust system for the quantitative determination of interactions between tumor cells and endothelium. Adherent cells can be easily quantified on a fluorescence plate reader. |
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CytoSelect BrdU Cell Proliferation ELISA Kit |
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| MBS168339-5x96Assays | MyBiosource | 5x96Assays | EUR 2900 |
CytoSelect BrdU Cell Proliferation ELISA Kit |
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| MBS168339-96Assays | MyBiosource | 96Assays | EUR 630 |
CytoSelect Cell Viability and Cytotoxicity Assay |
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| MBS168166-5x96Assays | MyBiosource | 5x96Assays | EUR 2090 |
CytoSelect Cell Viability and Cytotoxicity Assay |
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| MBS168166-96Assays | MyBiosource | 96Assays | EUR 460 |
CytoSelect 96-well Cell Transformation Assay |
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| MBS169037-5x96Assays | MyBiosource | 5x96Assays | EUR 3200 |
CytoSelect 96-well Cell Transformation Assay |
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| MBS169037-96Assays | MyBiosource | 96Assays | EUR 845 |
CytoSelect Tumor Transendothelial Migration Assay |
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| MBS169012-24Assays | MyBiosource | 24Assays | EUR 880 |
CytoSelect Tumor Transendothelial Migration Assay |
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| MBS169012-5x24Assays | MyBiosource | 5x24Assays | EUR 4060 |
CytoSelect 24-Well Cell Co-Culture System |
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| MBS168183-24Assays | MyBiosource | 24Assays | EUR 530 |
CytoSelect 24-Well Cell Co-Culture System |
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| MBS168183-5x24Assays | MyBiosource | 5x24Assays | EUR 1935 |
CytoSelect 96-well Phagocytosis Assay (Zymosan) |
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| MBS168370-5x96Assays | MyBiosource | 5x96Assays | EUR 3170 |
CytoSelect 96-well Phagocytosis Assay (Zymosan) |
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| MBS168370-96Assays | MyBiosource | 96Assays | EUR 820 |
CytoSelect 96-well Cell Invasion, Fluorometric |
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| MBS168452-5x96Assays | MyBiosource | 5x96Assays | EUR 4250 |
CytoSelect 96-well Cell Invasion, Fluorometric |
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| MBS168452-96Assays | MyBiosource | 96Assays | EUR 920 |
CytoSelect 24-well Cell Invasion, Fluorometric |
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| MBS168704-12Assays | MyBiosource | 12Assays | EUR 720 |
CytoSelect 24-well Cell Invasion, Fluorometric |
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| MBS168704-5x12Assays | MyBiosource | 5x12Assays | EUR 3330 |
CytoSelect 384-well Cell Transformation Assay, Fluorometric |
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| CBA-145 | Cell Biolabs | 384 assays | EUR 1208.4 |
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Description: Our CytoSelect 384-Well Cell Transformation Assay uses a modified soft agar 3D matrix to support the formation of colonies by neoplastic cells. Quantitation of cell transformation is performed on a fluorescence plate reader. |
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CytoSelect 384-well Cell Transformation Assay, Fluorometric |
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| CBA-145-5 | Cell Biolabs | 5 x 384 assays | EUR 4681.2 |
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Description: Our CytoSelect 384-Well Cell Transformation Assay uses a modified soft agar 3D matrix to support the formation of colonies by neoplastic cells. Quantitation of cell transformation is performed on a fluorescence plate reader. |
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CytoSelect 24-well Cell Haptotaxis Assay (8 um), FN-coated, Colorimetric |
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| MBS168739-12Assays | MyBiosource | 12Assays | EUR 685 |
CytoSelect 24-well Cell Haptotaxis Assay (8 um), FN-coated, Colorimetric |
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| MBS168739-5x12Assays | MyBiosource | 5x12Assays | EUR 3150 |
CytoSelect 24-well Cell Haptotaxis Assay (8 um), FN-coated, Fluorometric |
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| MBS168876-12Assays | MyBiosource | 12Assays | EUR 685 |
CytoSelect 24-well Cell Haptotaxis Assay (8 um), FN-coated, Fluorometric |
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| MBS168876-5x12Assays | MyBiosource | 5x12Assays | EUR 3150 |
CytoSelect 48-Well Cell Contraction Assay Kit |
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| MBS169268-48Assays | MyBiosource | 48Assays | EUR 770 |
CytoSelect 48-Well Cell Contraction Assay Kit |
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| MBS169268-5x48Assays | MyBiosource | 5x48Assays | EUR 3545 |
CytoSelect 24-well Cell Haptotaxis Assay (8 um), COL-coated, Colorimetric |
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| MBS168697-12Assays | MyBiosource | 12Assays | EUR 685 |
CytoSelect 24-well Cell Haptotaxis Assay (8 um), COL-coated, Colorimetric |
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| MBS168697-5x12Assays | MyBiosource | 5x12Assays | EUR 3150 |
CytoSelect 24-well Cell Haptotaxis Assay (8 um), COL-coated, Fluorometric |
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| MBS169224-12Assays | MyBiosource | 12Assays | EUR 685 |
CytoSelect 24-well Cell Haptotaxis Assay (8 um), COL-coated, Fluorometric |
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| MBS169224-5x12Assays | MyBiosource | 5x12Assays | EUR 3150 |
CytoSelect™ 96-Well Hematopoietic Colony Forming Cell Assay (5 x 96 assays) |
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| CBA-320-5 | Cell Biolabs | 5 x 96 assays | EUR 1885 |
CytoSelect™ 24-Well Cell Migration Assay (3 µm, Fluorometric Format), Trial Size |
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| CBA-103-T | Cell Biolabs | 4 assays | EUR 240 |
CytoSelect™ 96-well In Vitro Tumor Sensitivity Assay (Soft Agar Colony Formation) |
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| CBA-150 | Cell Biolabs | 96 assays | EUR 670 |
CytoSelect™ 96-well In Vitro Tumor Sensitivity Assay (Soft Agar Colony Formation) |
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| CBA-150-5 | Cell Biolabs | 5 x 96 assays | EUR 2935 |
CytoSelect Cell Proliferation Assay Reagent (Fluorometric) |
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| CBA-250 | Cell Biolabs | 10 mL | EUR 490.8 |
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Description: Cell Biolabs? CytoSelect Cell Proliferation Assay Reagent (Fluorometric) provides a fluorometric format for measuring and monitoring cell proliferation. Cells can be plated and then treated with compounds or agents that affect proliferation. Cells are then incubated with the proliferation reagent. Upon entering metabolically active live cells, the non-fluorescent proliferation reagent is converted into a bright red fluorescent form. An increase in cell proliferation is accompanied by increased fluorescent signal, while a decrease in cell proliferation (and signal) can indicate the toxic effects of compounds or suboptimal culture conditions. The assay principles are basic and can be applied to most eukaryotic cell lines, including adherent and non-adherent cells and certain tissues. This cell proliferation reagent can be used to detect proliferation in bacteria, yeast, fungi, protozoa as well as cultured mammalian and piscine cells. The kit contains sufficient reagents for the evaluation of 960 assays in ten 96-well plates or 192 assays in eight 24-well plates. |
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CytoSelect Cell Proliferation Assay Reagent (Colorimetric) |
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| MBS169040-10mL | MyBiosource | 10mL | EUR 455 |
CytoSelect Cell Proliferation Assay Reagent (Colorimetric) |
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| MBS169040-5x10mL | MyBiosource | 5x10mL | EUR 1875 |
CytoSelect 24-well Laminin Cell Invasion, Colorimetric |
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| CBA-110-LN | Cell Biolabs | 12 assays | EUR 714 |
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Description: The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the morbidity and mortality of cancers. Cell invasion requires several distinct cellular functions including adhesion, motility, detachment, and extracellular matrix proteolysis. Our CytoSelect Cell Invasion Assays utilize precoated inserts to assay the invasive properties of tumor cells. Invasive cells can be quantified in 24-well plates on either a standard microplate reader or a fluorescence plate reader. Inserts are precoated on the top of the membrane with Laminin. |
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CytoSelect 96-well Phagocytosis Assay (Red Blood Cell) |
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| MBS168645-5x96Assays | MyBiosource | 5x96Assays | EUR 3355 |
All predicted interactions are validated by literature filtering, GO-based evaluation, and KEGG Pathway enrichment evaluation. This examine will encourage the identification of potential targets for simpler anti-dengue drug discovery.